MULTIPLE TIME POINTS OF TRANSCRIPTOME ANALYSIS REVEALED ALTERED GENES INVOLVED IN MAINTAINING HIBERNATION IN THE HYPOTHALAMUS OF TAMIAS SIBIRICUS

Multiple time points of transcriptome analysis revealed altered genes involved in maintaining hibernation in the hypothalamus of Tamias sibiricus

Hibernation, an adaptive mechanism to extreme environmental conditions, is prevalent among mammals.Its main characteristics include reduced body temperature and metabolic rate.However, the mechanisms by which hibernating animals re-enter deep sleep during the euthermic phase to sustain hibernation remain poorly understood.We selected the Tamias sib

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Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults.

Ocular light exposure has important influences on human health and well-being through modulation of circadian rhythms and sleep, as well as neuroendocrine and cognitive functions.Prevailing patterns of light exposure do not optimally engage Washing Machine Power Module these actions for many individuals, but advances in our understanding of the und

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Redox driven B12-ligand switch drives CarH photoresponse

Abstract CarH is a coenzyme B12-dependent photoreceptor involved in regulating carotenoid biosynthesis.How light-triggered cleavage of the B12 Co-C bond culminates in Apparel CarH tetramer dissociation to initiate transcription remains unclear.Here, a series of crystal structures of the CarH B12-binding domain after illumination suggest formation o

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The role of Atg16 in autophagy, anthocyanin biosynthesis, and programmed cell death in leaves of the lace plant (Aponogeton madagascariensis).

Aponogeton madagascariensis, commonly known as the lace plant, produces leaves that form perforations by programmed cell death (PCD).Leaf development is divided into several stages beginning with "pre-perforation" furled leaves enriched with red pigmentation from anthocyanins.The leaf blade is characterized by a series of grids known as areoles bou

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